STAT5b in LGL leukemia - a novel therapeutic target?
نویسندگان
چکیده
منابع مشابه
STAT5b in LGL leukemia – a novel therapeutic target?
The activation of signal transducer and activator of transcription (STAT) family genes, especially STAT5 and STAT3, has been established in multiple solid tumors and hematological malignancies. Recently we discovered somatic activating STAT3 mutations in 40% of T-cell large granular lymphocytic (LGL) leukemia and 30% of NK-cell LGL leukemia patients (Koskela, Eldfors et al. NEJM, 2012, 17;366(2...
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ژورنال
عنوان ژورنال: Oncotarget
سال: 2013
ISSN: 1949-2553
DOI: 10.18632/oncotarget.1035